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what are the causes of papillary eccrine adenoma and what are the causes of papillary eccrine adenoma

what are the causes of papillary eccrine adenoma and what are the causes of papillary eccrine adenoma

Etiology of papillary eccrine adenoma

Etiology of papillary eccrine adenoma

First, the cause of the disease:

The causes of papillary eccrine adenoma are quite complex, including heredity, natural aging, female hormones, personal physique and so on.

1. Related to heredity: This disease is a nevus-like tumor, sometimes with family history.

2. It may be related to endocrine disorders.

Second, the pathogenesis:

1. Histochemical studies showed that syringoma contained phosphorylase and hydrolase which originated from eccrine glands. Many cystic ducts and solid cords of epidermal cells were found in the upper and middle part of the dermis, embedded in the fibrous matrix. The wall of cystic duct is often lined with two layers of cells, which are mostly flat. The inner layer cells are occasionally vacuolar. The outer wall cells of some ducts protrude and bend outward, shaped like commas or tadpoles. In successive sections, these cystic ducts can be seen to be connected to the dilating sac of the intradermal duct, but not to the secretory segment of the apocrine gland below.

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