symptoms of trichoepithelioma, early symptoms and signs of trichoepithelioma
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Typical symptoms: skin color or yellow papules or nodules, spherical or conical, hard.
Related symptoms: papular nodules
The damage is multiple or single.
1. Multiple trichoepithelioma is a dominant hereditary benign tumor lesion, which is a solid papule or nodule with multiple smooth and slightly transparent surface. The diameter of a single skin lesion is 2 ~ 4mm, which is flesh-colored or reddish, and its center is slightly sunken. Often in groups but isolated. Skin lesions usually occur on the face, especially near the upper lip, paranasal sulcus and eyelid, and other parts such as head, neck and trunk can also occur. Skin lesions occur in children or adolescents, and are more common in women.
2. Single trichoepithelioma is a non-hereditary tumor, which is rare compared with multiple trichoepithelioma. It often occurs on the face, but it can also occur on the head, neck, trunk, upper arm and thigh. The skin lesions are solid flesh-colored raised nodules, often less than 2cm. It is more common in children or young people. Sometimes huge solitary trichoepithelioma can be seen, and the diameter of skin lesions can reach several centimeters, often occurring in the thigh or perianal region. It is more common in middle-aged and elderly people.
The skin lesions of solitary trichoepithelioma are solid fleshy protuberant nodules, often less than 2cm. Most of them are trichoepithelioma with firm papules or nodules with smooth and slightly transparent surface. Combined with pathological examination, diagnosis can be made.
The multiple hair of this disease has certain clinical characteristics, which are multiple, symmetrical and small nodules or papules with normal skin color. It is easy to occur on the face, and begins to be seen in children or young people, with a tendency of family onset. The rash persists without change, but new rashes can occur slowly. Single hair has no clinical features, which can only be confirmed by pathological examination.
This disease should be distinguished from Pringle disease (tuberous sclerosis), syringoma, basal cell nevus syndrome, etc. It is sometimes difficult to differentiate in clinic, but tuberous sclerosis often has other complications, which are helpful for differential diagnosis. Syringoma mainly occurs around eyes, and can occur in neck, chest and back, usually with less damage and consistent size. Basal cell nevus syndrome also occurs in the face, but the disease has no prone site, and can be broken early, and often accompanied by bone and central nervous system abnormalities. If pathological examination is made, the differentiation is more reliable. Pathologically, it should be differentiated from keratinizing basal cell carcinoma, nodular basal cell carcinoma, hair adenoma and hair follicle tumor.
Single hair trichoepithelioma is often mistaken for non-pigmented intradermal nevus, because it has no special clinical manifestations, so it should be examined pathologically. However, in pathological examination, differential diagnosis will encounter difficulties, especially keratinizing basal cell tumor, which can hardly be distinguished from individual visual fields and needs comprehensive observation before diagnosis. About 30% of the specimens in Gray's case were initially misdiagnosed as basal cell tumors.
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