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symptoms of pneumocystis carinii, early symptoms and signs of pneumocystis carinii

symptoms of pneumocystis carinii, early symptoms and signs of pneumocystis carinii

Symptoms of pneumocystis carinii

Early symptoms: Insidious onset, rapid breathing is the earliest respiratory symptoms, and later on, dry cough, dyspnea, flapping of the nose, cyanosis, etc.

Late symptoms: rapid onset, rapid onset of fever, cough, dyspnea, cyanosis, etc., but rare rales. Those with a short course can die within 4 to 8 days.

Related symptoms: fever, cough, difficulty breathing, cyanosis

1. Symptoms

There are two types of infections with clinical manifestations.

1. Popular type is also known as infant type. It is more common in infants with low birth weight, malnutrition or congenital immunodeficiency. Insidious onset, increased breathing is the earliest respiratory symptom, and later symptoms such as dry cough, dyspnea, flapping of the nose, and cyanosis. The fatality rate of those who were not treated in time was 50%.

2. The sporadic type is also known as the child-adult type. It is more common in people with weak or defective immune function. The onset is sudden, fever, cough, dyspnea, cyanosis, etc. appear quickly, but there are few rales. Those with a short course can die within 4 to 8 days. X-ray chest changes are often later than clinical manifestations. If there is no specific treatment, the fatality rate is as high as 90% to 100%, regardless of whether it is an adult or a child. The X-ray findings of the two types of lungs showed diffuse, double-sided stripes or spot-like shadows. Pneumonia and the lung base are less affected. It can develop rapidly to cause pulmonary consolidation, and the consolidation lesions often have extensive or localized atelectasis after emphysema. In some cases, pneumothorax, pleural fluid, and shadow of lung nodules can be seen. Arterial blood oxygen partial pressure is often lower than 10.7kPa (80mmHg), CO2 partial pressure is normal or low, and arterial blood pH often increases.

In addition to the above clinical manifestations, the following inspections are also required:

1. The white blood cell count of the blood picture is normal or elevated, mostly (15-20)*109/L, the classification is normal or the nucleus shifts to the left, and the eosinophils may increase slightly.

2. Pathogen inspection The sputum inspection is the most convenient and safe. It can be stained and microscopically inspected after centrifugal precipitation and smears. Bronchoalveolar lavage fluid or lung biopsy specimens can be diagnosed with Pneumocystis carinii trophozoites and cysts. In recent years, the application of various staining methods (such as toluidine blue staining) and PCR technology has greatly increased the detection rate.

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