symptoms of X-interlocking ichthyosis, early symptoms and signs of X-interlocking ichthyosis
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Symptoms of X-interlocking ichthyosis
Typical symptoms: Except palms and soles, the whole body skin is involved. Outside the folds around axillary, elbow fossa, popliteal fossa, groin, anal circumference and external genitalia, the damage is slightly light because of relatively damp.
Related symptoms: pigmented skin lesions and scales
Almost all of them are found in men. The disease occurs at birth or shortly after birth. Limbs, face, neck, trunk and buttocks can often be seen with large and significant scales, with neck, face and trunk being the heaviest involved. Individual cases or severe cases can spread to elbow fossa, armpit and popliteal fossa. The appearance of palms and plantars is normal or slightly thickened, and the scales are often brown and sticky. Mild scales can be seen in front of arms and tibia in female carriers. Ocular slit lamp examination showed obvious corneal posterior wall or elastic layer opacity in some patients. Male patients may have cryptorchidism and testicular cancer. Skin lesions do not decrease with age.
Diagnosis can be made according to clinical manifestations, skin lesions and histopathological characteristics.
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