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occupational scleroderma examination, occupational scleroderma diagnosis

occupational scleroderma examination, occupational scleroderma diagnosis

Common examination of occupational scleroderma

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Anti-polymyositis-l antibodyBlood vesselDermatosisAnti-polymyositis...
Plain films of bones and joints of limbsBone upper limb lower limb--Used to confirm fractures...
Immunopathological examinationWhole body--Immunopathological examination...
X-ray examination found osteolytic changes, which often began with the absorption and thinning of bone cortex in the early stage, and could lead to complete absorption and fracture in the later stage, often involving phalanges, ulna and radius and sacroiliac joints of hands.

Histopathology: The skin histopathology mainly showed flat epidermal nails, increased collagen fibers and broken elastic fibers in dermis.

It can be manifested as poverty, hematuria, proteinuria, tubular urine, increased erythrocyte sedimentation rate, decreased serum albumin and increased globulin.

ANA positive rate > 90%, mainly dot type and nucleolar type, about 20% anti-RNP antibody positive, about 50%-90% CREST patients anti-centromere antibody (ACA) positive, (labeled antibody), 20%-40% systemic sclerosis patients serum SCL-70 antibody positive, (labeled antibody), 30% RF, peripheral blood T cell total normal or slightly lower, in which T helper cells increased, T inhibitor cells decreased.

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