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Visiting department: reproductive health treatment cost: about (1000-5000 yuan) in the top three hospitals in the city. Cure rate: treatment method: drug treatmentGeneral treatment of immune infertility
First, Western medicine treatment of immune infertility
1. For men
For infertility caused by high concentration of sperm antibody in male autoimmunity, the following methods can be used for treatment:
1) Immunosuppressive therapy
Use adrenocortical hormone, treat with a small dose for a long time according to the specific situation, or use a large dose of shock therapy, and share the same room when sperm antibody drops to a certain extent in the body, so as to increase the chance of conception.
2) Artificial insemination
Semen is collected, and then antibodies attached to sperm surface are washed away with special sperm washing solution for artificial insemination.
3) Use Lecone Rebound Therapy
According to the physiological activity characteristics of testosterone, the application of large dose of testosterone first inhibits spermatogenic epithelium, and then stops using testosterone, so that spermatogenic epithelium produces more sperm after releasing inhibition, which is testosterone rebound therapy. When the number of sperm decreases, the antibody titer also decreases or disappears. Choosing to have the same room after the number of sperm rebounds and the antibody has not increased obviously can increase the chance of conception.
4) Treatment of primary disease
2. For women
Immune infertility caused by antibodies in women can be treated by condom intercourse or taking corticosteroids immunosuppressants at the same time.
1) Avoid antigen contact
Using condoms every time you have sex can avoid further stimulation of sperm antigen to the woman. When the sperm antibody level of the woman drops, the patient is encouraged to have condom sex or carry out artificial insemination during ovulation.
2) Immunosuppressive method
Adrenal cortical hormone drugs have anti-inflammatory and interfering macrophage toxicity. Therefore, it can be used to treat immune infertility.
3) Intrauterine insemination
When sperm antibody in cervical mucus interferes with fertility, the semen of her husband can be treated in vitro to separate high-quality sperm for artificial insemination. This method avoids the restriction of sperm passage by sperm antibody in cervical mucus.
4) In vitro fertilization
Sperm and egg are cultured and fertilized in vitro, and implanted into uterine cavity 3-5 days after fertilization. Therefore, sperm does not need to contact with female reproductive tract containing sperm antibody before fertilization. After fertilization, due to the protective effect of zona pellucida of pregnant eggs, sperm antibodies cannot attack pregnant eggs, and then pregnant eggs are implanted.
Syndrome Differentiation and Treatment of Immune Infertility
Second, TCM treatment of immune infertility
There is no special record of this disease in ancient Chinese medicine books, which belongs to infertility. According to pulse syndrome and TCM syndrome differentiation, it can be divided into kidney yin deficiency type, kidney yang deficiency type and damp-heat type. Traditional Chinese medicine therapy is specifically the following method.
1. Kidney yin deficiency type
Menstruation is early, the amount is small, the color is red without blood clots, or the menstruation is still normal, but the waist and legs are weak, dizziness, insomnia, acute and noisy temperament, dry mouth, five vexations and heat, hot flashes in the afternoon, red tongue, less fur and thin pulse. Common treatment prescriptions: Angelica sinensis 10g, Rehmannia glutinosa 10g, Radix Paeoniae Rubra 15g, Cuscuta chinensis 20g, Ligustrum lucidum 20g, Glycyrrhiza uralensis Fisch 10g, Salvia miltiorrhiza 15g, Fructus barbarum 15g, Polyporus umbellatus 15g, Raspberry 15g and Huaishan 15g.
2. Kidney-yang deficiency type
In the late menstruation, the amount is small and the color is light, or the menstruation is rare, amenorrhea, the complexion is dark, the waist is sore and the legs are soft, the libido is indifferent, the urine is clear and long, the stool is untrue, the tongue is pale and the fur is white, and the pulse is thin or late. Commonly used treatments: Codonopsis pilosula 15g, Chuanxiong 10g, Herba Epimediae 15g, Raspberry 15g, Glycyrrhiza uralensis 10g, Cuscuta chinensis 20g, Barbarum 10g, Atractylodes macrocephala 15g, Angelica sinensis 10g, Radix Paeoniae Rubra 15g, Salvia miltiorrhiza 15g and Ligustrum lucidum 15g.
3. Damp-heat type
Dry mouth, bitter or sour mouth, bright red menstruation, excessive leukorrhagia, yellow or yellow white color, sticky quality, poor appetite, tiredness and fatigue, sleep-loving, little yellow urine, red tongue, yellow greasy or thick fur, and slightly numerous pulse. Commonly used therapeutic prescriptions: Scutellaria baicalensis Georgi 15g, Coptis chinensis 5g, Artemisia wormwood 30g, Salvia miltiorrhiza 15g, Radix Paeoniae Rubra 15g, Cortex Paeoniae Rubra 10g, Radix Codonopsis 10g, Fructus Barbari 10g, Rhizoma Dioscoreae 15g, Cortex Moutan 10g and Polyporus All the above patients took 1 dose of traditional Chinese medicine every day, and 2 months was a course of treatment.
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