examination of clear cell sweat gland adenoma and diagnosis of clear cell sweat gland adenoma
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Common examination of clear cell sweat gland adenoma
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- Fungal histopathologyWhole bodyDepartment of Ophthalmology and Health CareFungal histopathology...
- Immunopathological examinationWhole body--Immunopathological examination...
1. Immunopathological examination.
2. Fungal histopathology.
This tumor is well-defined, may be capsulated, and consists of lobulated masses, located in dermis and extending into subcutaneous tissue. There are often tubular cavities of different sizes in lobulated masses. The tubular cavity is lined with cubic ductal cells or columnar secretory cells. Secretory cells occasionally indicate active secretion of decapitation secretion. Two types of cells can be seen in the solid part of tumor. One is polygonal cells with round nucleus, slightly basophilic cytoplasm, and some cells are spindle-shaped with long nucleus. The other kind of cells are often round, with extremely transparent cytoplasm, so that the cell membrane is clearly visible and the nucleus is dark and small. In different tumors, the proportion of them is quite different, and there are transitional cells between the two types. Clear cells contain a considerable amount of glycogen, but there are a considerable amount of PAS-positive and amylase-resistant substances around them. In some tumors there are keratinocytes that form keratinous beads, while in others clusters of squamous cells are arranged around the small cavity, which is lined with a clear eosinophilic protective membrane, so it looks like eccrine duct.
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