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Differential diagnosis of ovarian infertility
1. Cervical infertility
Glucose and its nutrients in cervical fluid (CM) have great influence on the survival and motility of sperm when crossing cervix. The interaction between sperm and cervix or fluid is an important key link for sperm survival and function. Infertility caused by cervical factors accounts for 5% ~ 10% of the total infertility.
2. Tubal infertility
The fallopian tube is of great significance to fertility. Under the regulation of sex hormones and nervous system, the periodic changes in tissue structure, physiology and biochemistry are of great significance to the interception of eggs, the transportation of fertilized eggs, and the provision of suitable environment for nutrition and metabolism of fertilized eggs.
3. Vulvovaginal infertility
Infertility caused by vaginal and vaginal diseases accounts for about 5%-10% of infertility, Vagina is a container for sexual behavior and containing semen. If organic or functional diseases occur in vulva and vagina, it will affect the normal entry and storage of sperm and semen in vagina or lead to infertility due to changes in the internal environment of vulva and vagina, which will affect the function of sperm.
4. Uterine infertility
Simple uterine infertility is rare, accounting for only about 2% of infertile patients. Uterine malformations such as saddle-shaped uterus mediastinal or semi-mediastinal uterus, bicorn uterus, monohorn uterus and uterine dysplasia can cause infertility; Excessive uterine fibroids or adhesion, traction and passage caused by inflammation of reproductive organs or pelvic endometriosis can also cause infertility; Endometrial tuberculosis is not easy to be found by endometrial tissue sections after the lesion is static, but it affects embryo implantation; Traumatic injury of endometrium, such as multiple curettage or too deep curettage, also leads to the inability of fertilized eggs to implant.
5. Abnormal chromosomal infertility
Chromosome abnormalities can cause gonadal dysplasia or reproductive tract abnormalities such as adrenal gonadal syndrome and congenital ovarian dysplasia (Turner syndrome).
6. Immune infertility
Immune infertility refers to the normal ovulation and reproductive function of patients without pathogenic factors, and the routine examination of spouse semen is in the normal range, but there is evidence of anti-fertility immunity in infertile couples. Immune infertility accounts for 5%-7%. There are two kinds of immune infertility: anti-sperm and anti-zona pellucida. At present, the pathogenesis of the latter is not clear, so the clinical immune infertility mostly refers to anti-sperm rabbit plague infertility.
7. Infertility caused by other factors
Age: More than 60% of couples are pregnant within 3 months after marriage. After that, the fertility decreased with the increase of couple's age and marriage time, that is, the longer the infertility time after marriage, the gradual decline of pregnancy rate.
Nutrition: You can get pregnant only if you get 22% of your body weight. Excessive obesity can cause hypogonadism and fertility decline, but the exact role of fat content in human reproductive function is still unclear.
Diet: Trace elements are closely related to sexual hormone secretion and reproductive system diseases.
Tobacco, alcohol and narcotic drugs
8. Mental infertility
Couples often have deep disappointment emotional mental injury can cause central catecholamine and endorphin secretion changes, resulting in anovulation and amenorrhea.
9. Environmental factors, environmental and occupational pollution
Such as noise, textile dyes, mercury and dry cleaning chemicals, can affect female fertility.
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