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  4. how to diagnose and differentiate immune infertility-easily confused diseases of immune infertility

how to diagnose and differentiate immune infertility-easily confused diseases of immune infertility

how to diagnose and differentiate immune infertility-easily confused diseases of immune infertility

Diagnosis of immune infertility

1. Ovarian infertility

It is one of the common causes of female infertility. 15%-20% of infertile women have ovulation defects, which are often accompanied by menstrual disorder, anovulation or luteal insufficiency and unruptured follicle luteinization syndrome.

2. Tubal infertility

The fallopian tube is of great significance to fertility. Under the regulation of sex hormones and nervous system, the periodic changes in tissue structure, physiology and biochemistry are of great significance to the interception of eggs, the transportation of fertilized eggs, and the provision of suitable environment for nutrition and metabolism of fertilized eggs.

3. Vulvovaginal infertility

Infertility caused by vaginal and vaginal diseases accounts for about 5%-10% of infertility, Vagina is a container for sexual behavior and containing semen. If organic or functional diseases occur in vulva and vagina, it will affect the normal entry and storage of sperm and semen in vagina or lead to infertility due to changes in the internal environment of vulva and vagina, which will affect the function of sperm.

4. Uterine infertility

Simple uterine infertility is rare, accounting for only about 2% of infertile patients. Uterine malformations such as saddle-shaped uterus mediastinal or semi-mediastinal uterus, bicorn uterus, monohorn uterus and uterine dysplasia can cause infertility; Excessive uterine fibroids or adhesion, traction and passage caused by inflammation of reproductive organs or pelvic endometriosis can also cause infertility; Endometrial tuberculosis is not easy to be found by endometrial tissue sections after the lesion is static, but it affects embryo implantation; Traumatic injury of endometrium, such as multiple curettage or too deep curettage, also leads to the inability of fertilized eggs to implant.

5. Abnormal chromosomal infertility

Chromosome abnormalities can cause gonadal dysplasia or reproductive tract abnormalities such as adrenal gonadal syndrome and congenital ovarian dysplasia (Turner syndrome).

6. Cervical infertility

Glucose and its nutrients in cervical fluid (CM) have great influence on the survival and motility of sperm when crossing cervix. The interaction between sperm and cervix or fluid is an important key link for sperm survival and function. Infertility caused by cervical factors accounts for 5% ~ 10% of the total infertility.

7. Infertility caused by other factors

1) Age

More than 60% of couples are pregnant within 3 months after marriage. After that, the fertility decreased with the increase of couple's age and marriage time, that is, the longer the infertility time after marriage, the gradual decline of pregnancy rate.

2) Nutrition

You can get pregnant only if you get 22% of your body weight. Excessive obesity can cause hypogonadism and fertility decline, but the exact role of fat content in human reproductive function is still unclear.

3) Diet

Trace elements are closely related to sexual hormone secretion and reproductive system diseases.

Tobacco, alcohol and narcotic drugs

8. Mental infertility

Couples often have deep disappointment emotional mental injury can cause central catecholamine and endorphin secretion changes, resulting in anovulation and amenorrhea.

9. Environmental factors, environmental and occupational pollution

Such as noise, textile dyes, mercury and dry cleaning chemicals, can affect female fertility.

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