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1. Routine urine examination
There may be a small amount of protein, red blood cells, white blood cells, and sometimes casts.
2. Surrounding blood
(1) The total number of white blood cells decreases when the disease begins
(2) There are abnormal lymphocytes, and the blood picture returns to normal 1 week after the fever
(3) The percentage of neutrophils is also reduced, and there is a significant shift of nucleus to the left
3. Serum immunological examination
Take double sera for complement fixation test, neutralization test or hemagglutination inhibition test. The hemagglutination inhibition test is more sensitive, and the complement fixation test is the most specific. The titer of the complement fixation antibody of a single specimen during the recovery period is up to 1:32 or more has diagnostic significance; double serum titer increases by more than 4 times to confirm the diagnosis.
4. Virus isolation
Take blood from early patients, inoculate it in Aedes albopictus cell strain (C6/36), and isolate the virus to be identified by type-specific neutralization test or hemagglutination inhibition test.
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